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1 20/11/2010 Seminar on PRODRUGS FOR SITE SPECIFIC DRUG DELIVERY PRESENTED BY Mr. Shriram Nikam (M.phrm Sem-1) (Pharm. Chem) GUIDED BY:Dr. M. S. BHATIA ( M.phrm Ph.D) Bharati Vidyapeeth College of Pharmacy, Kolhapur 2 Abbreviations          BBB GABA E.g ADEPT ± GDEPT ± AbAb-E i.v ASA GITGIT- Blood brain barrier Gama-aminobutyric acid GamaExample Antibody directed enzyme prodrug therapy Gene directed enzyme prodrug therapy Antibody enzyme conjugate Intravenous Amino salicylic aci
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  11  22 Seminar on PRODRUGS FOR SITE SPECIFIC DRUG DELIVERYBharati Vidyapeeth College of Pharmacy, Kolhapur GUIDED BY:-Dr. M. S. BHATIA( M.phrm Ph.D)PRESENTED BYMr. Shriram Nikam(M.phrm Sem-1)(Pharm. Chem) 20/11/2010  33 AbbreviationsAbbreviations  BBBBBB -- Blood brain barrier Blood brain barrier   GABAGABA -- GamaGama--aminobutyric acidaminobutyric acid  E.gE.g -- ExampleExample  ADEPTADEPT ±  ± Antibody directed enzyme prodrug therapyAntibody directed enzyme prodrug therapy  GDEPTGDEPT ±  ± Gene directed enzyme prodrug therapyGene directed enzyme prodrug therapy  AbAb--EE -- Antibody enzyme conjugateAntibody enzyme conjugate  i.vi.v -- IntravenousIntravenous  ASAASA -- Amino salicylic acidAmino salicylic acid  GITGIT-- Gastro intestinal tractGastro intestinal tract  44 CON TE  N TS CON TE  N TS  Introduction  O  bjectives  Types  Prodrugs For Site Specificity  Targeting to Brain  Targeting to Kidney  Targeting to C olon  Targeting to Tumor   C onclusion and References
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